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Biote Testosterone Replacement Therapy for Men: What You Need to Know

Biote Testosterone Replacement Therapy for Men: What You Need to Know

In this type, your pituitary gland produces more luteinizing hormone (LH) and follicle-stimulating hormone (FSH) (known as gonadotropins) in response to low testosterone levels. The high levels of these hormones would normally tell your testicles to produce more testosterone and sperm. However, if you have damaged (most commonly related to prior chemotherapy) or missing testicles, they can’t respond to the increased levels of gonadotropins. As a result, your testicles make too little or no testosterone and sperm. As hormone levels fluctuate depending on activity levels, diet, and the time of day, doctors usually take two different blood samples before noon. They may sometimes also ask for imaging studies and additional tests, such as tests for luteinizing hormone and follicle stimulation hormone, to determine the cause of the low testosterone levels.

Some of these medications are used off-label to increase testosterone. “Taking testosterone can cause proliferation of your red blood cells,” says Dubin. That may increase the risk of blood clots, though the data are mixed.

Testosterone pellets have a long duration of action; however, they require an in-office procedure. Given the plethora of treatment options and direct-to-consumer pharmaceutical advertising, it is crucial for pharmacists to understand differences between these therapies and educate patients on their profiles and administration techniques. Beyond statistical significance, clinical relevance is another key factor. In analyzing the literature, it is imperative to determine whether or not statistically significant results are clinically meaningful.

With Biote, we individualize and personalize your therapy dose based on the labs we draw. We also consider your age, weight, and activity level along with these labs. This objective data helps produce personalized dosing for you that we can then tinker with over time. We’re not just throwing a dart against the wall and hoping that we land on the right dose. Even more troubling, studies suggest that more and more men in their late thirties and early forties are experiencing low T. We have testosterone receptors all over our body—from the brain and the eyes down to our skin, bone marrow, lymphoid tissues, blood, and male and female reproductive systems.

Patients who are on long-acting SQ pellets require two separate assessments of testosterone to determine the dose and frequency required. The first testosterone measurement should be obtained two to four weeks after initial implant to determine if the number of inserted pellets needs to be increased or decreased to achieve the appropriate therapeutic level. Patients who are on long-acting IM testosterone (testosterone undecanoate) should have blood work tested once steady state levels have been achieved. Testosterone undecanoate is typically re-administered at a time point 4 weeks after initial dosing and then every 10 weeks thereafter. As with short-acting IM testosterone injections, the general recommendation is mid-cycle testing, after equilibration, and halfway between the first two 10-week injections.

A doctor will also monitor changes in symptoms and side effects at 3 and 6 months after the initial treatment and then annually. Testosterone pellets are small plastic pellets that doctors implant under the skin. The pellets dissolve slowly and can deliver TRT for 3–6 months. The dosage varies between individuals and a person should discuss this with their doctor prior to the first implantation. However, these benefits were quite modest and went away with the discontinuation of TRT. Around half of the participants in the 2019 study still had bone mineral density in the ranges of osteopenia or osteoporosis while on TRT.

A relatively small number of men experience immediate side effects of testosterone supplementation, such as acne, disturbed breathing while sleeping (worsening sleep apnea), breast swelling or tenderness, or swelling in the ankles. Doctors also watch out for high red blood cell counts, which could increase the risk of clotting. The quality of the pellets that providers can use varies dramatically. I’m excited to partner with Biote because I believe in its commitment to investing in the highest-quality products and its overall philosophy regarding hormone replacement therapy.

So direct-to-consumer telemedicine services, and even for-profit men’s health clinics, may feel more approachable, less stigmatizing, or more convenient, Dubin points out. Most studies don’t provide enough detail to know exactly when testosterone measurements were taken or how testosterone was measured. While many studies (often company funded) suggest that some of those ingredients can boost testosterone, the results don’t hold up to scrutiny. “Low libido is the most sensitive symptom for detecting low testosterone,” says Dubin. View medical records, test boost elite and max nitric oxide results, book appointments, manage family’s care, pay bills and more.

“The form of testosterone we ultimately decide upon involves shared decision-making with the patient based on their goals and preferences,” says Dr. Muthigi. Non-Discrimination PolicyMen’s Health Boston complies with applicable Federal civil rights laws and does not discriminate on the basis of race, color, national origin, age, disability, sex, sexual orientation, or gender identity. If your treatment includes an injectable medication, we’ll make sure you receive comprehensive education on how to use it. Patients often practice giving themselves their first dose under our supervision to get any questions answered.